In-Situ Sterilizable Lab Scale Fermenter

Total Capacities

3-150 Liters

Working Volume

2.0 Liters to 115 Liters

Design:

Designed as per ASME standards

to comply with the required

pressure in vessels and in

Bioprocess.

Type:

SS316L vessel with glass

window and SS304 jacket,

In-situ Sterilizable(SIP & CIP)

Controls:

Auto temperature/RPM:20-

2800/pH/DO2 with cascade

control/ Antifoam/Air flow/auto

sterilization through Modular

Micro-controller & PID Controls.

Other probes for out-gases

etc available on demand.

Drive:

Top driven and direct coupled

Motor with single/double

mechanical

seal.

Steam/Air

filtration

0.22 µm PTFE filter Cartridge

with SS316L housing plus

0.45/0.22µm prefilter with SS

housing.

Control Panel:

Multi colored PLC/TFT Touch

Screen/Graphic display Control

panel with HMI for monitoring

and control of pH/Temp/DO2

and Agitation.

D/H Ratio

1:2.5 Automatic control for

Temperature, Sterilization,

Agitation, Aeration pH DO,

Pressure, Antifoam, Acid,

Base, Feed,MFC etc.

Vessel and Jacket

Design Parameters

Max. Working Temp for vessel:

150 deg C and for Jacket:

140deg C Working Pressure for

vessel: 3.0 Bar and for Jacket:

3.75 Bar Design Temp. for

vessel will be 150 dig and for

Jacket 150 deg C Design

Pressure for vessel will be 3.0

Bar and for jacket 4.0 Bar

Provision of Ports

On the top plate with safety

valve, agitator, gas outlet,

light glass, pressure gauges,

additional ports with a collar,

air sparger, air by pass, 3 nos

. of standard ports for acid,

Alkali and feed. At 1/3 height

of shell/vessel from bottom

provided with 25 mm standard

ports for pH ,DO ,temperature

probes and a sampling valve

in the bottom dish, Jacket -

provided with ports for

steam/water entry, standard

ports, Jacket drain etc.

Agitator Assembly

Shaft, 3/4 nos. of Ruston

turbine impellers, single/double

mechanical seal. Motor

& RPM are customized as

per requirement. Accuracy

1 RPM with VFD/Speed controller

card etc.

Top Plate

Bolted to the shell. Bottom

shell welded to the shell,

jacket cover 80% of the

total height, All parts in

contact with culture made

of SS 316 L, Jacket and

spiral – SS 304 , “O” rings

made of EDPM, silicone

Pipe Line Fittings

and Accessories

Inlet/outlet cartridge filters

with SS316L housing and

pressure gauges,. meter

for flow measurement etc

Steam/Water

Connection

With diaphragm control

valves to control sterilization

temperature, All the valves

in the lines connected to

the jacket are pneumatically

operated from the control panel.

Base frame

Suitable base frame.

MOC: SS304 to house

the vessel, agitator assembly

along with pipe rack etc.